N8‐Acetylspermidine: A Polyamine Biomarker in Ischemic Cardiomyopathy With Reduced Ejection Fraction
نویسندگان
چکیده
منابع مشابه
New biomarker in heart failure with reduced ejection fraction.
eart failure is a serious condition because of the structural and/or functional cardiac disorders,1–3 in which not only heart failure with preserved ejection fraction (HFpEF) but also heart failure with reduced ejection fraction (HFrEF) are substantially involved.4,5 Because of the poor prognosis of patients, especially those with HFrEF,6 various therapeutic options have been developed during t...
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OBJECTIVE To observe the effect and safety of cardiac rehabilitation (CR) exercise in ischemic cardiomyopathy and to compare the results between patients with preserved left ventricular ejection fraction (LVEF) and reduced LVEF. METHODS Patients with ischemic cardiomyopathy with LVEF <50% were included as subjects. The patients were classified into the preserved LVEF (pLVEF; LVEF 41%-49%) gro...
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BACKGROUND Remote ischemic preconditioning (RIPC) induced by transient limb ischemia confers multi-organ protection and improves exercise performance in the setting of tissue hypoxia. We aimed to evaluate the effect of RIPC on exercise capacity in heart failure patients. METHODS We performed a randomized crossover trial of RIPC (4×5-minutes limb ischemia) compared to sham control in heart fai...
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Heart failure with reduced ejection fraction is a clinical syndrome of dysp nea, exercise intolerance and/or edema resulting from an impairment of ejec tion of blood, usually documented by a left ventricular ejection fraction of 40% or less on echocardiography.1,2 Cor on ary artery disease is a major cause; therefore, stress testing or, in the pres ence of angina, coronary angiography shoul...
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The study of Bax et al. (1) that is reported in this issue of The Journal of Nuclear Medicine addresses an important clinical issue. Specifically, in the setting of left ventricular failure with markedly reduced ejection fraction (mean 6 SD, 30 6 6 in this study), selection of patients with ischemic heart disease who will benefit from coronary revascularization often is problematic. The authors...
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ژورنال
عنوان ژورنال: Journal of the American Heart Association
سال: 2020
ISSN: 2047-9980
DOI: 10.1161/jaha.120.016055